Endocrine Abstracts

Aim: The aim of the present study was to compare version 7 of ATA risk calculating tool, developed for the staging of well differentiated thyroid cancers,and is used commonly in the clinical practice with its version 8 developed in 2018 with respect to clinical staging.Material and method: 295 patients followed with the diagnosis of well differentiated thyroid cancer were included in the present study. According to pathology reports and clinical data, th...

Introduction: The etiology of gender dysphoria is still unclear. Although prior studies have shown trans men have higher androgen levels than cisgender women, they all concluded unselected populations. Our purpose to perform this study is to evaluate transmen’s hormone profile and metabolic status to compare cisgender women in a more selected population. This is the first case-controlled study to compare anthropometric, metabolic, and endocrinological parameters of drug-n...

Purpose: Thyroid autoimmune diseases occur more frequently in women than men. A previous study reveals that exogenous testosterone may have a protective effect on thyroid autoimmunity in men with Hashimoto’s thyroiditis. But no study has determined whether sex hormones produce any effect on thyroid antibody titreş in women. The primary study aim was to assess whether exogenous testosterone affects thyroid autoimmunity in trans-men with increasing testosterone levels....

Background: Obesity and diabetes are major causes of morbidity and mortality that are increasing all over the world. As obesity is a major risk factor for type 2 diabetic patients, weight loss has an important place in the treatment of type 2 diabetic patients. In our study, it’s aimed to evaluate the effects of exenatide and laparoscopic sleeve gastrectomy (LSG) in obese diabetic patients on the clinical and laboratory parameters.Subjects and metho...

Introduction: Spondyloepiphyseal dysplasia congenita (SEDC) is a rare congenital disease of skeletal system,which is characterized by short stature, shortage of trunk and mostly affect vertebral column and epiphysis of long bones. In this case report, we aimed to represent a patient complaining of short stature and referred to our hospital,who was detected to have an early onset osteoporosis accompanied by proximal femoral aplasia; in the light of literature.<p class="abst...

Background: It is known that obesity-related renal damage,regardless of type 2 diabetes and hypertension, may improve by weight-loss modalities. In this study, we aimed to evaluate the effect of bariatric surgery on glycemic and lipid parameters, anthropometric measurements, renal parameters and urine NGAL (Neutrophil Gelatinase-Associated Lipocalin) levels in obese diabetic or nondiabetic patients who has not respond to medical treatmentMaterials and me...

Aim: Hashimoto Thyroiditis (HT); is the most common form of hpothyroidism in iodine-sufficient regions. Both genes and and environmental factors are involved in the immunopathological process of HT. Our aim in this study is to determine the prevalence of Thyrothropin Receptor (TSHR), Cytotoxic T Lypmhocyte Antigen-4 (CTLA-4) and Interleukin-1 Receptor Antagonist (IL-1RN) gene polymorphisms associated with HT in Turkish population and the relationship of genotype characteristic...

Objectives: Preoperative imaging studies are being commonly used in primary hyperparathyroid patients to increase cure rate and to decrease complication rate of surgery. In this study we correlated the surgical outcomes with localization studies performed by various radiologists.Method: A total of 174 patients with primary hyperparathyroidism in which healing of hypercalcemia achieved by parathyroidectomy were evaluated retrospectively. Since our hospita...

Introduction: Hashimoto’s thyroiditis (HT) is caused by a variety of genes, cytokines, receptors, and environmental factors. A series of enzymes known as type 1 and type 2 deiodinases (D1, D2) are in charge of converting thyroxine (T4) into triiodothyronine (T3). It is believed that the low free T3 (fT3) levels caused by D2 polymorphism may result in thyroid autoimmunity through the induction of inflammation. However, iodothyronine deiodinase (DIO) gene polymorphism and H...

Introduction: Renin-angiotensin-aldosterone system was shown to be activated in severe COVID-19 infection. We aimed to investigate the relation between angiotensin converting enzyme (ACE) levels, ACE gene polymorphism, type 2 diabetes (T2DM), and hypertension (HT), and the prognosis of COVID-19 infection.Methods: Clinical features of adult patients with SARS-CoV-2 infection diagnosis were analyzed. ACE gene analysis and ACE level measur...